Latex constituents from Calotropis procera (R. Br.) display toxicity upon egg hatching and larvae of Aedes aegypti (Linn.)

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Latex constituents from Calotropis procera (R. Br.) display toxicity upon egg hatching and larvae of Aedes aegypti (Linn.).

Calotropis procera R. Br. (Asclepiadaceae) is a well-known medicinal plant with leaves, roots, and bark being exploited by popular medicine to fight many human and animal diseases. This work deals with the fractionation of the crude latex produced by the green parts of the plant and aims to evaluate its toxic effects upon egg hatching and larval development of Aedes aegypti. The whole latex was...

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Limonoids as larvicidal components against mosquito larvae (Aedes aegypti Linn.).

The study focussed on four limonoids (calodendrolide, harrisonin, pedonin and pyroangolensolide) as larvicidal components against mosquito 2nd instar larvae of the species Aedes aegypti Linn. senso stricto. Since pyroangolensolide is close to calodendrolide in structure, it was synthesized through reduction of calodendrolide with chromium(II) chloride in acetone. Harrisonin and pedonin were ext...

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Phytochemical and Antibacterial Activity of Calotropis Procera (ait.) R. Br. Flowers

Phytochemical screening and antimicrobial activity of chloroform, acetone and methanolic extracts of Calotropis procera (Ait.) R. Br. (Asclepiadaceae) flowers were tested against various pathogens such as Salmonella paratyphi, S. paratyphi A, Bacillus subtilis, Bacillus thuringiensis, Proteus mirabilis, Proteus vulgaris, Pseudomonas aeruginosa, Staphylococcus aureus and Escherichia coli. Phytoc...

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Antioxidant, Cytotoxicity and Polyphenolic Content of Calotropis procera (Ait.) R. Br. Flowers

Oxidative stress has been implicated with the pathology of many diseases such as inflammatory conditions, cancer, diabetes and aging. In view of that an attempt was made to evaluate free radical scavenging activity, cytotoxic activity and polyphenolic content of methanolic extract of Calotropis procera flowers.Free radical scavenging activity was estimated using in vitro models like 1,1,-diphen...

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Calotropis procera Latex-Induced Inflammatory Hyperalgesia—Effect of Antiinflammatory Drugs

The milky white latex of plant Calotropis procera produces inflammation of the skin and mucous membranes on accidental exposure. It produces edema on local administration due to the release of histamine and prostaglandins and is associated with hyperalgesia. In the present study we have evaluated the antiedematous and analgesic activity of antiinflammatory drugs against inflammatory response in...

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ژورنال

عنوان ژورنال: Memórias do Instituto Oswaldo Cruz

سال: 2006

ISSN: 0074-0276

DOI: 10.1590/s0074-02762006000500004